Mehta {flexmix} | R Documentation |
For a 22-centre trial the number of responses and the total number of patients is reported for the control group and the group receiving a new drug.
data("Mehta")
A data frame with 44 observations on the following 4 variables.
Number of responses.
Total number of observations.
A factor indicating treatment with levels New
and
Control
.
A factor indicating the site/centre.
M. Aitkin (1999): Meta-analysis by random effect modelling in generalized linear models. Statistics in Medicine 18, pages 2343-2351.
C.R. Mehta, N.R. Patel and P. Senchaudhuri (1988): Importance sampling for estimating exact probabilities in permutational inference. Journal of the American Statistical Association 83, pages 999-1005.
data("Mehta") mehtaMix <- stepFlexmix(cbind(Response, Total-Response) ~ 1|Site, data=Mehta, nrep=5, k=3, model=FLXMRglmfix(family="binomial", fixed=~ Drug), control=list(minprior=0.04))