sphase {coin} | R Documentation |
S-phase fraction of tumor cells in breast cancer patients.
data("sphase")
This data frame contains the following columns:
S-phase fraction
recurrence free survival
censoring indicator: FALSE
means
censored, TRUE
is an event.
The data have been used to address the question whether a simple cutpoint in S-phase fraction can be used to discriminate between patients with good and bad prognosis (for example in Hothorn & Lausen, 2003).
J. Pfisterer, F. Kommoss, W. Sauerbrei, D. Menzel, M. Kiechle, E. Giese, M. Hilgarth \& A. Pfleiderer (1995). DNA flow cytometry in node positive breast cancer: Prognostic value and correlation to morphological and clinical factors. Analytical and Quantitative Cytology and Histology 7(6), 406–412.
Torsten Hothorn & Berthold Lausen (2003). On the exact distribution of maximally selected rank statistics. Computational Statistics \& Data Analysis 43, 121–137.
maxstat_test(Surv(RFS, event) ~ SPF, data = sphase) ### reproduce the test statistic reported in Hothorn & Lausen (2003) maxstat_test(Surv(RFS, event) ~ SPF, data = sphase, ytrafo = function(data) trafo(data, surv_trafo = function(x) logrank_trafo(x, ties.method = "HL")))