ocarcinoma {coin}R Documentation

Ovarian Carcinoma

Description

Survival times of 35 women suffering ovarian carcinoma at stadium II and IIA.

Usage

data("ocarcinoma")

Format

A data frame with 35 observations on the following 3 variables.

time

time in days.

event

censoring indicator: FALSE means censored, TRUE is an event.

stadium

a factor with levels II and IIA.

Details

Data from Fleming et al. (1980, 1984), reanalysed in Schumacher and Schulgen (2002).

Source

Thomas R. Fleming, Judith R. O'Fallon, Peter C. O'Brien \& David P. Harrington (1980). Modified Kolmogorov-Smirnov test procedures with applications to arbitrarily censored data. Biometrics 36, 607–625.

Thomas R. Fleming, Stephanie J. Green \& David P. Harrington (1984). Considerations of monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials 5, 55–66.

References

Martin Schumacher & Gabi Schulgen (2002), Methodik klinischer Studien: Methodische Grundlagen der Planung, Durchf\"uhrung und Auswertung. Springer, Heidelberg.

Examples


  ### logrank test with exact two-sided p-value
  lrt <- surv_test(Surv(time, event) ~ stadium, data = ocarcinoma,
                   distribution = "exact")

  ### the test statistic
  statistic(lrt)

  ### p-value
  pvalue(lrt)


[Package coin version 1.0-20 Index]