ellipse.profile {ellipse}R Documentation

Pairwise profile sketch

Description

This routine approximates a contour of a function based on the profile of that function.

Usage

ellipse.profile(x, which=c(1, 2), level=0.95, t=sqrt(qchisq(level, 2)), npoints=100)

Arguments

x An object of class profile, typically the result of the profile() function applied to a fit by the ms() general maximum likelihood procedure.
which Which pair of parameters to use.
level Assuming that the function is -2 times the log likelihood of a regular model, this specifies the confidence level for an asymptotic confidence region.
t The square root of the value to be contoured.
npoints How many points to use in the ellipse.

Details

This function uses the 4 point approximation to the contour as described in Appendix 6 of Bates and Watts. It produces the exact contour for quadratic surfaces, and good approximations for mild deviations from quadratic. If the surface is multimodal, the algorithm is likely to produce nonsense.

Value

An npoints x 2 matrix with columns having the chosen parameter names, which approximates a contour of the function that was profiled.

References

Bates and Watts (1988) Nonlinear Regression Analysis & its Applications

See Also

profile, ms, ellipse.nls

Examples

# Plot an approximate 95% confidence region for the Puromycin
# parameters Vm and K, and overlay the ellipsoidal region
data(Puromycin)
Purboth <- nls(formula = rate ~ ((Vm + delV * (state == "treated"))
  * conc)/(K + conc), data = Puromycin,
  start = list(Vm = 160, delV = 40, K = 0.05))
Pur.prof <- profile(Purboth)
plot(ellipse(Pur.prof,which=c('Vm','K')),type='l')
lines(ellipse(Purboth,which=c('Vm','K')),lty=2)